Myles played a main role in the comedy-romance film 2002 before then playing the role of Erika in the 2003 vampire film with , and reprised the character in its sequel, 2006.
Sophia Myles has Blue colored eyes.
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Her parents are Jane and Peter Myles, who is a vicar, a priest in the Anglican Church who is in charge of a parish and receives a salary, but not the tithes of the church.
Her father, Peter Myles, died on 21 March 2020 after contracting.